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Exercise Neuromodulation

Meaning

Exercise Neuromodulation is the process by which structured physical activity induces adaptive, beneficial changes in the function, structure, and communication pathways of the central and peripheral nervous systems. This includes the modulation of neurotransmitter synthesis and release, the enhancement of neurotrophic factors like Brain-Derived Neurotrophic Factor (BDNF), and the improvement of neurovascular coupling. Clinically, this phenomenon is leveraged to improve mood, enhance cognitive function, reduce neuro-inflammation, and restore optimal signaling across the hypothalamic-pituitary axes. It highlights exercise as a potent, non-pharmacological tool for brain health and endocrine balance.