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Exercise Mimetics Research

Meaning

Exercise mimetics research is a specialized field of molecular endocrinology and pharmacology dedicated to identifying and developing compounds that can pharmacologically replicate the beneficial metabolic, cardiovascular, and hormonal adaptations induced by physical exertion. These agents aim to activate the same intracellular signaling pathways, such as AMPK and sirtuins, that are stimulated by exercise, offering therapeutic potential for individuals unable to perform adequate physical activity. The goal is to confer the systemic health benefits, including improved insulin sensitivity and mitochondrial biogenesis, without the physical strain.