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Exercise-Induced Epigenetics

Meaning

Exercise-Induced Epigenetics describes the dynamic changes in gene expression that occur in response to physical activity without altering the underlying DNA sequence itself. These modifications, such as DNA methylation and histone acetylation, serve as a critical molecular link translating the beneficial effects of exercise into sustained physiological adaptations, including improved insulin sensitivity and enhanced mitochondrial biogenesis. This area of study reveals how lifestyle choices directly influence the readability of the genome, profoundly impacting metabolic and hormonal health over the lifespan. Understanding this mechanism provides a sophisticated rationale for personalized exercise prescriptions.