Exercise Induced Cortisol refers to the transient, physiological elevation in the circulating concentration of the primary glucocorticoid hormone, cortisol, that is observed during and immediately following periods of physical exertion. This hormonal response is a normal and necessary component of the body’s stress response, serving to mobilize energy substrates and modulate the initial inflammatory cascade. The magnitude and clearance rate of this increase are important clinical markers for assessing training load and overall recovery capacity.
Origin
This specific term is derived from clinical endocrinology and exercise biochemistry, combining the potent physiological stimulus (exercise) with the central hormonal response (cortisol). Cortisol is etymologically linked to the adrenal cortex, its site of synthesis, and its function as a stress regulator. The concept highlights the adrenal gland’s crucial role in mediating the metabolic demands and systemic stress imposed by physical activity.
Mechanism
Physical stress activates the hypothalamic-pituitary-adrenal (HPA) axis, initiating a cascade that leads to the release of corticotropin-releasing hormone (CRH) and subsequently adrenocorticotropic hormone (ACTH). ACTH then stimulates the adrenal cortex to synthesize and release cortisol. Cortisol’s primary function in this context is to maintain stable blood glucose levels by promoting hepatic gluconeogenesis and to ensure a controlled, adaptive inflammatory response in the damaged muscle tissue.
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