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Exercise and Androgen Receptors

Meaning

This term describes the dynamic interaction between physical activity and the density or sensitivity of androgen receptors (ARs), the intracellular proteins that bind to and mediate the actions of androgens like testosterone and dihydrotestosterone (DHT). Regular, appropriate exercise, particularly resistance training, is clinically understood to be a potent stimulus for increasing the expression and functionality of these receptors in target tissues, such as skeletal muscle. This enhanced receptor action allows the existing circulating androgen levels to exert a more significant biological effect, promoting anabolic outcomes and improved body composition.