A defined set of measurable physiological, biochemical, and functional biomarkers that correlate directly with the duration and quality of an individual’s healthy, high-performing life, emphasizing cognitive and physical capacity. These metrics move beyond traditional disease markers to quantify biological age and the reserve capacity of critical organ systems. They serve as actionable clinical targets for longevity-focused interventions.
Origin
This lexicon combines the business term “Executive,” denoting high-level function and performance, with the scientific concept of “Healthspan,” the period of life spent in good health. It represents the clinical translation of aging research into practical, performance-oriented wellness goals.
Mechanism
Tracking these metrics, which include indices of metabolic health, cardiovascular elasticity, hormonal signaling efficacy, and cellular senescence, allows for the precise evaluation of therapeutic efficacy. Interventions are designed to shift these markers toward the values associated with a younger, more resilient physiology. The ongoing measurement and iterative adjustment of protocols drive the optimization of the patient’s functional biological trajectory.
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