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Excitation-Contraction Coupling

Meaning

Excitation-Contraction Coupling, or ECC, is the fundamental physiological process that meticulously links the electrical excitation of an excitable cell membrane, typically in the form of an action potential, to the mechanical contraction of the muscle cell. This intricate, rapid sequence is absolutely essential for the proper function of all muscle types, including skeletal, smooth, and cardiac muscle, ensuring coordinated movement and adequate cardiac output. ECC serves as a critical biological junction where incoming neural or hormonal signals are reliably translated into a physical, contractile force.