What is the Origin of Evidence-Based Anti-Aging?

This term represents a maturation within the field of gerontology and regenerative medicine, demanding empirical validation for longevity claims. It contrasts with anecdotal approaches by requiring data derived from clinical trials or strong preclinical models, especially concerning sirtuin activation or senolytic clearance. The foundation is scientific rigor applied to lifespan extension.

What is the Mechanism of Evidence-Based Anti-Aging?

The mechanism involves targeting specific cellular processes known to drive senescence, such as telomere attrition, mitochondrial dysfunction, or chronic low-grade inflammation (inflammaging). Interventions may modulate NAD+ metabolism or optimize growth hormone/IGF-1 signaling within safe physiological limits. Success relies on modulating the fundamental molecular drivers of age-related decline.

Evidence-Based Anti-Aging ∞ Area

Evidence-Based Anti-Aging

Meaning

Evidence-Based Anti-Aging constitutes the clinical practice of applying interventions supported by rigorous scientific literature to mitigate the physiological hallmarks of aging and extend healthspan. This approach prioritizes interventions with demonstrable mechanistic plausibility and clinical outcome data over speculative modalities. We focus on validated longevity pathways.