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Estrogenomics

Meaning

Estrogenomics is a comprehensive, systems-level approach to studying the full spectrum of estrogen action, encompassing its synthesis, metabolism, receptor signaling, and genetic variation across the human population. This field integrates data from genomics, proteomics, and metabolomics to understand how individual genetic makeup influences estrogen’s role in health, disease, and therapeutic response. The clinical goal is to move beyond simple hormone level measurement toward a personalized understanding of estrogen’s impact on an individual’s biology, including cardiovascular, bone, and cognitive health.