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EstrogenNeuroprotection

Meaning

Estrogen Neuroprotection refers to the diverse and beneficial mechanisms by which the sex steroid hormone estrogen, primarily estradiol, exerts a safeguarding effect on the structure and function of the central nervous system. This protective action is crucial for maintaining neuronal viability, promoting essential synaptic plasticity, and defending against neurodegenerative processes and cerebral oxidative stress. Clinically, the concept is highly relevant to understanding post-menopausal cognitive changes and the potential therapeutic role of hormone optimization in maintaining brain health.