Skip to main content

Estrogen-Responsive Elements

Meaning

Estrogen-Responsive Elements, or EREs, are specific short sequences of DNA located in the promoter regions of genes whose transcription is regulated by estrogen hormones. These genetic elements act as docking sites for the activated estrogen receptor complex, serving as a critical control point for gene expression throughout the body. The presence and activity of EREs dictate which cellular functions are directly influenced by circulating estrogen levels.