What is the Origin of Estrogen Receptor Affinity?

This concept is central to pharmacology and steroid hormone biology, determining the efficacy of hormonal signaling.

What is the Mechanism of Estrogen Receptor Affinity?

Affinity dictates the concentration required to occupy a critical percentage of receptors; higher affinity allows for a greater downstream genomic or non-genomic effect at lower circulating concentrations.

Estrogen Receptor Affinity ∞ Area

Estrogen Receptor Affinity

Meaning

Estrogen Receptor Affinity quantifies the strength of the binding interaction between endogenous or exogenous estrogenic compounds and their cognate nuclear receptors.