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Estrogen Protective Effects

Meaning

Estrogen Protective Effects encompass the diverse range of beneficial, non-reproductive actions mediated by estrogens, primarily estradiol, across various physiological systems, including cardiovascular, skeletal, and neurological tissues. These effects are vital for maintaining systemic health, particularly in women and men with adequate estrogen balance. Key protective actions include promoting endothelial function, maintaining bone mineral density by inhibiting osteoclast activity, and supporting neurocognitive function through enhanced synaptic plasticity. A decline in estrogen, such as during menopause or with certain treatments, leads to the loss of these protective mechanisms, accelerating age-related deterioration.