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Estrogen Pellet Therapy

Meaning

Estrogen Pellet Therapy is a specialized method of hormone replacement that involves the subcutaneous implantation of small, solid pellets containing bioidentical estradiol or estrone into the adipose tissue. This unique delivery system provides a continuous, sustained release of the hormone directly into the systemic circulation over a period of several months, effectively bypassing the first-pass hepatic metabolism associated with oral formulations. It is clinically utilized to manage the systemic and local symptoms of estrogen deficiency, such as severe vasomotor instability and genitourinary atrophy.