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Estrogen Metabolite Management

Meaning

Estrogen Metabolite Management is the clinical strategy focused on influencing the specific metabolic pathways through which the body processes and eliminates estrogens, such as estradiol and estrone. The goal is to favor the production of beneficial, protective estrogen metabolites, like 2-hydroxyestrone, while minimizing the formation of potentially harmful, proliferative, or genotoxic metabolites, such as 4-hydroxyestrone. This management is crucial for mitigating hormone-sensitive health risks and maintaining long-term hormonal balance.