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Estrogen Metabolism SNPs

Meaning

Estrogen Metabolism SNPs (Single Nucleotide Polymorphisms) are common genetic variations in the DNA sequence of genes that encode the enzymes responsible for the synthesis, conjugation, and clearance of estrogen and its metabolites. These small, single-base pair changes can significantly alter the function of these enzymes, leading to variable rates of estrogen breakdown and the production of different estrogen metabolites. Clinically, identifying these SNPs is crucial for assessing an individual’s risk for estrogen-sensitive conditions and for tailoring nutritional or hormonal support strategies to promote a healthier balance of estrogen metabolites.