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Estrogen Metabolism Science

Meaning

Estrogen Metabolism Science is the specialized study of the complex biochemical pathways responsible for the synthesis, circulation, and breakdown of estrogen hormones, primarily estradiol, estrone, and estriol, within the body. This field investigates the enzymatic conversion of androgens into estrogens via aromatase, and the subsequent detoxification and clearance of estrogen metabolites, particularly through the liver. The balance of these metabolic pathways, which produce various active and inactive estrogen forms, is critical for reproductive health, bone density, and cancer risk modulation. Clinical assessment of this metabolism guides personalized hormonal interventions.