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Estrogen Metabolism Optimization

Meaning

Estrogen Metabolism Optimization is a clinical strategy focused on promoting the healthy and efficient breakdown and clearance of estrogen and its metabolites from the body. This process is critical because estrogen is metabolized into various intermediate forms, some of which are considered more proliferative or potentially harmful to cellular DNA than others. Optimization aims to favor the production of protective estrogen metabolites, such as the 2-hydroxyestrone pathway, while minimizing the accumulation of less favorable forms like 4- and 16-hydroxyestrone. Proper detoxification capacity is essential for maintaining long-term hormonal balance and cellular health.