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Estrogen Fluctuation Patterns

Meaning

Estrogen Fluctuation Patterns refer to the characteristic, predictable, and measurable changes in the circulating levels of estradiol and other estrogenic compounds over a defined period, most notably the menstrual cycle, but also across the lifespan, such as during perimenopause. Analyzing these dynamic patterns, rather than relying on a single static measurement, provides crucial insight into the functional integrity of the hypothalamic-pituitary-ovarian (HPO) axis and its downstream effects on bone density, mood, and cardiovascular health. Disruptions in the expected pattern are key indicators of endocrine dysregulation.