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Estrogen and Insulin Sensitivity

Meaning

Estrogen and Insulin Sensitivity describes the direct and protective influence of the steroid hormone estrogen, primarily 17β-estradiol, on the body’s ability to respond efficiently to the pancreatic hormone insulin. Enhanced insulin sensitivity means that target cells require less insulin to effectively facilitate glucose uptake from the bloodstream, leading to superior glycemic control and a reduced risk of metabolic dysfunction. This hormonal relationship is a critical component of female metabolic health, with sensitivity typically declining significantly post-menopause.