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Estrogen and Cognitive Health

Meaning

Estrogen and Cognitive Health describes the critical, multifaceted relationship between the sex steroid hormone estrogen, particularly estradiol, and its profound influence on various aspects of brain function and neuroprotection. Estrogen is known to modulate synaptic plasticity, cerebral blood flow, and neurotransmitter systems, supporting domains like verbal memory and executive function, especially in women. Declining estrogen levels, such as during the menopausal transition, are clinically linked to transient cognitive changes, emphasizing its role as a key neurosteroid. Maintaining optimal hormonal balance is a central focus for long-term brain vitality.