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Estradiol Titration Strategy

Meaning

A methodical, evidence-based approach to adjusting the dosage of a hormone replacement regimen, or an associated aromatase inhibitor, with the specific intent of achieving and maintaining circulating serum estradiol levels within a clinically defined optimal range. This strategy relies on frequent biochemical monitoring and symptom correlation to finely tune the estrogenic environment, balancing therapeutic efficacy with the mitigation of potential side effects. Precision dosing is paramount to support bone health, cardiovascular function, and neurocognitive well-being.