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Estradiol Synaptic Plasticity

Meaning

Estradiol Synaptic Plasticity describes the profound and rapid ability of the primary estrogen, estradiol (E2), to structurally and functionally modify the connections, known as synapses, between neurons within the brain. This neurobiological action is critically important for core cognitive functions, including the processes of memory formation, learning, and mood regulation, particularly within key brain regions like the hippocampus and prefrontal cortex. Estradiol functions as a powerful neurosteroid, influencing neuronal architecture and the overall speed and efficiency of signal transmission.