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Estradiol Supplementation

Meaning

Estradiol Supplementation is a clinical intervention involving the therapeutic administration of exogenous 17β-estradiol, the most potent and primary estrogen, to restore physiological levels typically diminished due to natural aging, menopause, or specific medical conditions. This treatment is a cornerstone of Hormone Replacement Therapy (HRT) for women, aiming to alleviate vasomotor symptoms, prevent bone density loss, and support urogenital and cognitive health. The goal is to safely replace the deficit, matching the body’s historical hormone profile as closely as possible. Treatment protocols require careful, individualized dosing and monitoring to ensure therapeutic efficacy and minimize risk.