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Estradiol Replacement Therapy

Meaning

Estradiol Replacement Therapy, or ERT, is a clinical intervention involving the exogenous administration of 17-beta estradiol, the most potent and primary estrogen, to compensate for its deficiency in the body. This therapy is typically utilized following menopause or surgical removal of the ovaries, aiming to restore physiological levels. It is specifically designed to alleviate vasomotor symptoms, prevent accelerated bone density loss, and support the integrity of estrogen-dependent tissues. Clinical decision-making necessitates careful assessment of individual risk factors and the patient’s comprehensive hormonal profile to ensure a personalized and safe regimen.