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Estradiol Progesterone Therapy

Meaning

A specific form of Hormone Replacement Therapy (HRT) for women, involving the clinical administration of both estradiol, the most potent form of estrogen, and progesterone, a key hormone of the luteal phase and pregnancy. This combination is typically prescribed to alleviate the vasomotor, genitourinary, and psychological symptoms associated with estrogen deficiency in menopause. The inclusion of progesterone is a critical clinical component for women with an intact uterus to mitigate the risk of endometrial hyperplasia associated with unopposed estrogen.