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Estradiol Neurotransmitters

Meaning

Estradiol Neurotransmitters refers to the complex, critical, and indirect modulatory influence that the primary sex steroid hormone, estradiol, exerts on the synthesis, release, and post-synaptic action of classical neurotransmitters within the central nervous system. Estradiol itself is a hormone, but its presence profoundly alters the functional balance of key neurotransmitter systems, including serotonin, dopamine, and GABA. This neurohormonal interplay is essential for the precise regulation of mood, cognitive processing, and the physiological stress response in both males and females.