Skip to main content

Estradiol Conversion Balance

Meaning

Estradiol Conversion Balance refers to the clinical objective of regulating the rate and extent to which androgens, primarily testosterone, are converted into the potent estrogen, estradiol (E2), by the aromatase enzyme. Maintaining this balance is crucial for both male and female hormonal health, as either excessive or insufficient E2 levels can lead to adverse metabolic, cardiovascular, and skeletal health outcomes. A precise balance ensures the beneficial effects of both androgens and estrogens are realized without the complications associated with endocrine dominance or deficiency.