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Estradiol Concentration Management

Meaning

Estradiol concentration management is the clinical practice of carefully monitoring and adjusting the circulating levels of 17-beta estradiol (E2), the most potent endogenous estrogen, to maintain a specific, healthy range for an individual patient. This management is essential for preserving critical physiological functions, including bone mineral density, cardiovascular endothelial health, central nervous system integrity, and urogenital tissue maintenance in both sexes. The primary goal is to achieve the beneficial effects of E2 while meticulously avoiding the risks associated with either deficient or excessively high concentrations.