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Estradiol Brain Function

Meaning

Estradiol Brain Function refers to the multifaceted neurobiological roles of 17beta-estradiol, the most potent naturally occurring estrogen, in maintaining the structure, signaling, and overall health of the central nervous system. Beyond its reproductive roles, estradiol acts as a potent neurosteroid, influencing mood, cognition, memory consolidation, and neuroprotection. Adequate levels are essential for synaptic plasticity, cerebral blood flow regulation, and the modulation of neurotransmitter systems, particularly serotonin and dopamine. This function is vital for cognitive longevity and mental well-being across the lifespan.