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Estradiol and Memory

Meaning

Estradiol, the primary estrogen, significantly influences cognitive functions, particularly information retention processes, across the lifespan in both biological females and males, though its effects are more pronounced and studied in females. This neurosteroid modulates synaptic plasticity, neurogenesis, and neurotransmitter systems critical for learning and information retention within brain regions like the hippocampus and prefrontal cortex.