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Erythropoiesis-Stimulating Agents

Meaning

Erythropoiesis-Stimulating Agents (ESAs) are a class of pharmaceutical compounds, typically synthetic forms of the endogenous hormone erythropoietin, used clinically to treat anemia by promoting the production of red blood cells. These agents are essential therapeutic tools in managing chronic conditions, particularly anemia associated with chronic kidney disease or chemotherapy, where the body’s natural hormonal signaling for red cell generation is compromised. Proper administration requires careful clinical monitoring of hemoglobin levels to balance efficacy with cardiovascular risk.