Skip to main content

ERK/MAPK Pathway

Meaning

The ERK/MAPK Pathway, standing for Extracellular signal-Regulated Kinase/Mitogen-Activated Protein Kinase pathway, is a pivotal intracellular signaling cascade that transduces external stimuli into a variety of cellular responses. This complex relay system is a fundamental component of cellular communication, influencing crucial processes such as cell proliferation, differentiation, and survival. In the context of hormonal health, the pathway is often activated by peptide hormones and growth factors, mediating their effects on tissue maintenance, wound healing, and even the development of certain endocrine-related cancers. Its dysregulation can contribute significantly to age-related pathologies.