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Eplerenone

Meaning

Eplerenone is a prescription pharmaceutical agent classified as a selective aldosterone receptor antagonist (SARA), primarily used in the management of hypertension and heart failure following a myocardial infarction. It functions by specifically blocking the mineralocorticoid receptor (MR), thereby preventing the actions of the hormone aldosterone, which typically promotes sodium and water retention and potassium excretion. Its selective action provides therapeutic benefit with a lower risk of certain steroid-related side effects compared to non-selective agents.