Epitalon is a synthetic tetrapeptide, specifically Ala-Glu-Asp-Gly, which is structurally analogous to the naturally occurring pineal gland peptide epithalamin. It is primarily studied for its potential role in regulating the pineal gland’s function and influencing the body’s circadian rhythms and aging processes. Its clinical relevance lies in its potential application within longevity protocols and age-management strategies.
Origin
Epitalon was developed in the 1980s by the Russian scientist Professor Vladimir Khavinson and his team, based on their extensive research into the pineal gland and its peptide fractions. The research sought to isolate and synthesize the active components responsible for the pineal gland’s anti-aging and regulatory effects.
Mechanism
The primary mechanism of action is thought to involve the upregulation of telomerase activity, the enzyme responsible for maintaining and elongating telomeres, which are protective caps on the ends of chromosomes. By potentially preserving telomere length, Epitalon may contribute to increased cellular lifespan and improved tissue regeneration, influencing the production of other regulatory hormones like melatonin.
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