Skip to main content

Epigenomic Impact

Meaning

Epigenomic impact refers to the influence of environmental, nutritional, and lifestyle factors on gene expression without altering the underlying DNA sequence itself. These modulatory changes, such as DNA methylation and histone modification, determine which genes are actively transcribed and which remain silenced. Understanding this impact is crucial in longevity and hormonal health, as the epigenome acts as the dynamic interface between an individual’s genetic blueprint and their lived experience. A significant Epigenomic Impact can either promote healthspan or accelerate age-related decline by altering the function of key metabolic and endocrine genes.