What is the Origin of Epigenetics and Hair?

Epigenetics combines the Greek prefix epi- meaning "upon" or "in addition to" with genetics, literally meaning "in addition to the genes." The field emerged to explain how identical genetic codes can lead to diverse cellular phenotypes, such as different hair types or patterns of baldness. The study of this relationship provides a molecular link between lifestyle and the visible characteristics of hair health.

What is the Mechanism of Epigenetics and Hair?

Epigenetic mechanisms directly control the accessibility of the DNA to the transcription machinery within the hair follicle cells. For instance, high levels of dihydrotestosterone (DHT) can influence epigenetic markers, leading to the miniaturization of scalp follicles and the subsequent thinning of hair. Modifiable lifestyle factors can positively influence these epigenetic tags, potentially optimizing the gene expression profile for healthier, more robust hair growth.

Epigenetics and Hair ∞ Area

Epigenetics and Hair

Meaning

Epigenetics and Hair refers to the study of heritable changes in gene expression that do not involve alterations to the underlying DNA sequence, specifically as these changes influence hair follicle development, cycling, and morphology. Environmental factors, including nutrition, stress, and hormonal shifts, can induce epigenetic modifications like DNA methylation and histone modification. These modifications ultimately determine which genes related to hair growth and pigmentation are actively expressed or silenced.