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Epigenetic Signatures

Meaning

Epigenetic Signatures are specific, heritable patterns of chemical modifications to DNA or its associated proteins (histones) that influence gene expression without altering the underlying DNA sequence. These molecular patterns, such as DNA methylation or histone acetylation, function as a dynamic interface between the genome and the environment, including hormonal milieu and lifestyle factors. Analyzing these signatures provides a high-resolution view of biological aging and disease risk, often reflecting the cumulative impact of an individual’s life experience on their physiology.