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Epigenetic Signaling Modification

Meaning

Epigenetic Signaling Modification refers to the non-genetic, heritable changes in gene expression—such as DNA methylation and histone modification—that alter how cells interpret and respond to hormonal and environmental cues without changing the underlying DNA sequence. In the context of longevity, optimizing these modifications is a key therapeutic strategy aimed at restoring youthful gene expression patterns in response to vital endocrine signals. These molecular adjustments profoundly influence cellular identity and functional capacity across the lifespan.