Epigenetic Signaling Influence describes how external factors, including hormones, nutrients, and environmental exposures, modify gene activity without changing the underlying DNA sequence itself. This mechanism allows the body to adapt gene expression based on current physiological needs. It is the interface between environment and genome.
Origin
This terminology is foundational to modern molecular biology, originating from the study of how cells maintain specialized functions over time. It highlights regulatory layers above the DNA code.
Mechanism
Influence occurs through chemical tags like methylation or acetylation of histones surrounding the DNA helix. These modifications alter chromatin structure, making specific genes more or less accessible to the transcriptional machinery, thereby regulating the production of proteins essential for hormonal signaling and cellular maintenance.
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