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Epigenetic Rheostat Modulation

Meaning

Epigenetic rheostat modulation refers to the therapeutic or lifestyle-based manipulation of the epigenome—the layer of chemical tags on DNA and histones—to adjust the expression level of specific genes, acting much like a dimmer switch or rheostat. This concept recognizes that while the genetic code is fixed, its expression is dynamic and can be fine-tuned by environmental and nutritional factors. Clinically, this modulation is a key strategy for optimizing health and longevity by influencing disease-associated gene activity.