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Epigenetic Reprogramming Aging

Meaning

Epigenetic Reprogramming Aging is the intentional manipulation of the chemical modifications to DNA and associated proteins (histones) that regulate gene expression without altering the underlying DNA sequence, specifically targeting changes associated with biological aging. This process seeks to reverse or mitigate the accumulation of detrimental epigenetic ‘noise’ or errors, such as aberrant DNA methylation patterns, that drive cellular senescence and functional decline. Successful reprogramming aims to restore a more youthful, stable gene expression profile, thereby extending healthspan and cellular resilience.