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Epigenetic Repair Windows

Meaning

Epigenetic Repair Windows are specific, time-dependent physiological states, often coinciding with deep sleep or periods of controlled metabolic stress like fasting, during which cellular machinery is maximally engaged in correcting DNA and histone modifications. This is a critical process for maintaining genomic integrity and controlling gene expression patterns associated with cellular aging and disease risk. Optimizing these windows is a key strategy in longevity medicine and is fundamentally linked to robust hormonal signaling. Failure to adequately utilize these periods accelerates biological aging.