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Epigenetic Performance Factors

Meaning

Epigenetic Performance Factors are dynamic, non-genetic mechanisms that regulate gene expression, influencing physiological function, healthspan, and longevity, often in response to lifestyle and environmental inputs. These factors do not alter the underlying DNA sequence but act as regulatory “switches” that determine which genes are turned “on” or “off,” thereby affecting performance in areas like metabolism, cognitive function, and cellular repair. Examples include DNA methylation patterns and histone modifications, which can be measured to calculate a person’s biological age, often termed their “epigenetic clock.” Optimizing these factors through targeted interventions represents a frontier in personalized health and anti-aging medicine.