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Epigenetic Pattern Maintenance

Meaning

Epigenetic Pattern Maintenance refers to the ongoing biological process of preserving the stability and integrity of chemical modifications to DNA and associated histone proteins that regulate gene expression without altering the underlying DNA sequence. This precise preservation of the epigenome is essential for ensuring that cells maintain their correct identity and functional phenotype over time, preventing the accumulation of errors that drive cellular senescence and age-related pathology. Successful maintenance is a hallmark of biological longevity and is critical for cellular resilience and tissue repair mechanisms.