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Epigenetic Longevity Markers

Meaning

These markers are specific, quantifiable biochemical modifications to DNA or its associated proteins that influence gene expression without altering the underlying DNA sequence, serving as indicators of biological aging and longevity potential. They include DNA methylation patterns, histone modifications, and non-coding RNA profiles, which collectively reflect an individual’s accumulated environmental and lifestyle exposures. Clinically, measuring these epigenetic clocks provides a more accurate assessment of biological age compared to chronological age, offering a precise target for anti-aging interventions.