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Epigenetic Control Inputs

Meaning

Epigenetic Control Inputs are the non-genetic molecular signals—derived from diet, chronic stress, physical exercise, and the circulating hormonal milieu—that directly influence gene expression patterns without causing any alteration to the underlying DNA nucleotide sequence. These critical inputs include factors that drive DNA methylation, histone modification, and non-coding RNA activity, acting as the dynamic interface between the external environment and the inherited genome. Understanding and modulating these inputs is paramount for precision health and optimizing long-term cellular function.