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Epigenetic Command Centers

Meaning

Epigenetic Command Centers is a conceptual term referring to specific genomic regions or cellular components that exert disproportionately strong control over the overall epigenetic landscape and gene expression program of a cell. These centers are often comprised of regulatory elements like promoters, enhancers, and insulator regions, along with the machinery that controls DNA methylation and histone modifications. Their coordinated function dictates cellular identity, differentiation, and the response to environmental and hormonal signals. Maintaining the integrity of these centers is paramount for long-term cellular health and longevity.