Quantitative biological measures, typically derived from DNA methylation patterns across the genome, used to estimate an individual’s biological age, often diverging from chronological age due to environmental and hormonal influences.
Origin
This term combines “Epigenetics,” the study of heritable phenotype changes that do not involve alterations in the DNA sequence, with the concept of a measurable timeline.
Mechanism
These clocks operate by assessing methylation status at specific CpG sites, which are known to correlate strongly with age; fluctuations in key hormones can modulate the activity of DNA methyltransferases, thereby accelerating or decelerating the epigenetic age trajectory.
A longevity physician assesses biological age by integrating epigenetic clocks, hormonal panels, and functional tests to create a systems-level health portrait.
We use cookies to personalize content and marketing, and to analyze our traffic. This helps us maintain the quality of our free resources. manage your preferences below.
Detailed Cookie Preferences
This helps support our free resources through personalized marketing efforts and promotions.
Analytics cookies help us understand how visitors interact with our website, improving user experience and website performance.
Personalization cookies enable us to customize the content and features of our site based on your interactions, offering a more tailored experience.