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Epigenetic Clock Metrics

Meaning

Epigenetic Clock Metrics are quantitative measures derived from analyzing DNA methylation patterns at specific genomic locations, which collectively serve as highly accurate biological age predictors. These metrics, such as the Horvath or Hannum clocks, provide a more informative assessment of an individual’s true biological age compared to their chronological age. The discrepancy between these two ages, known as age acceleration or deceleration, is clinically significant as it correlates strongly with future morbidity, healthspan, and all-cause mortality risk. Tracking these metrics offers a powerful tool for monitoring the efficacy of longevity interventions.